SCHEMBL6538679

SCHEMBL6538679

Nc1cc(C(c2ccc(OCc3ccco3)c(N)c2)(C(F)(F)F)C(F)(F)F)ccc1OCc1ccco1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.44
CNR2 P34972 1/20 0.36
MAPT P10636 3/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
LMNA P02545 1/20 0.36
ATM Q13315 1/20 0.36
MGLL Q99685 1/20 0.35
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
SLC1A1 P43005 1/20 0.34
MRGPRX4 Q96LA9 1/20 0.34
ALDH1A1 P00352 3/20 0.33
RAB9A P51151 2/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
KMT2A Q03164 1/20 0.33
NPC1 O15118 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ADORA3 P0DMS8 1/20 0.32
MGMT P16455 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6538693 0.79 GAA (0.53) GAAMAPTL3MBTL1ATMMGLL
SCHEMBL23456206 0.74 GAA (0.57) GAAMAPTL3MBTL1LMNASLC1A3
SCHEMBL6538245 0.73 GAA (0.47) GAACNR2MAPTL3MBTL1MGLL
SCHEMBL17787263 0.71 MAPT (0.38) GAAMAPTL3MBTL1LMNAATM
SCHEMBL6538671 0.70 GAA (0.53) GAAMAPTL3MBTL1LMNAMGLL
SCHEMBL18072321 0.69 L3MBTL1 (0.42) GAAMAPTL3MBTL1LMNAATM
SCHEMBL9443798 0.69 L3MBTL1 (0.53) GAAMAPTL3MBTL1LMNAATM
SCHEMBL8308770 0.68 GAA (0.58) GAAMAPTL3MBTL1LMNAMRGPRX4
SCHEMBL5906237 0.67 L3MBTL1 (0.55) GAAMAPTL3MBTL1LMNAATM
SCHEMBL27717006 0.66 L3MBTL1 (0.46) GAAMAPTL3MBTL1LMNAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6709804-B2 Printed wiring board and semiconductor device and processes to prepare the same RIKEN (JP) 2004-03-23 US disclosed
US-20030194621-A1 Polyamic acid or a polyimide which has substituents having a cis-diene structure at the side chains, e.g., cyclopentadiene-, furan- or thiophene-groups RIKEN (JP) 2003-10-16 US disclosed
US-6528231-B1 Photosensitive resin composition can form a resin layer having excellent heat resistance RIKEN (JP) 2003-03-04 US disclosed