Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1A | P36894 | 3/20 | 0.38 |
| ▸ | ACVRL1 | P37023 | 3/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.38 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539323 | 0.78 | DDB1 (0.40) | BMPR1AACVRL1ACVR1BMPR1BTGFBR1 | |
| SCHEMBL6538762 | 0.73 | TP53 (0.38) | HSD11B1TP53POLBKDM4EKMT2A | |
| SCHEMBL6539242 | 0.68 | HTR2A (0.39) | BMPR1AACVRL1ACVR1BMPR1BTGFBR1 | |
| SCHEMBL6539735 | 0.66 | HTR2A (0.41) | BMPR1AACVRL1ACVR1BMPR1BTGFBR1 | |
| SCHEMBL6538291 | 0.65 | BRD4 (0.39) | POLBDDB1CRBNKMT2AKDR | |
| SCHEMBL5150930 | 0.65 | TP53 (0.40) | BMPR1AACVRL1ACVR1BMPR1BTGFBR1 | |
| SCHEMBL5149029 | 0.64 | TP53 (0.44) | BMPR1AACVRL1ACVR1BMPR1BTGFBR1 | |
| SCHEMBL6539443 | 0.64 | CRBN (0.34) | BMPR1AACVRL1ACVR1BMPR1BTGFBR1 | |
| SCHEMBL6538758 | 0.63 | PDE10A (0.38) | BMPR1AACVRL1ACVR1BMPR1BTGFBR1 | |
| SCHEMBL5147958 | 0.63 | ADORA2A (0.39) | BMPR1AACVRL1ACVR1BMPR1BTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067955-A1 | Pyridazinone compound and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067955-A1 | Pyridazinone compound and pharmaceutical use thereof | ADORA1, ADORA2A, P2RX5 | BMPR1A 2100/4885ACVRL1 1836/4885ACVR1 1613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.