Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.34 |
| ▸ | MTOR | P42345 | 5/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538915 | 1.00 | PPARD (0.36) | PPARDTAAR1PIK3CAMTORRCE1 | |
| SCHEMBL6539865 | 0.87 | PPARD (0.36) | PPARDTAAR1PIK3CARCE1ACACB | |
| SCHEMBL6539804 | 0.87 | GSK3B (0.36) | PPARDTAAR1RCE1ACACBACACA | |
| SCHEMBL6539849 | 0.87 | PPARD (0.36) | PPARDTAAR1PIK3CARCE1ACACB | |
| SCHEMBL6539798 | 0.87 | GSK3B (0.36) | PPARDTAAR1RCE1ACACBACACA | |
| SCHEMBL6540457 | 0.87 | PPARD (0.41) | PPARDTAAR1PIK3CAMTORRCE1 | |
| SCHEMBL6235990 | 0.81 | PPARD (0.43) | PPARDTAAR1RCE1ACACBACACA | |
| SCHEMBL6539329 | 0.80 | PPARD (0.41) | PPARDTAAR1PIK3CAMTORRCE1 | |
| SCHEMBL6208169 | 0.79 | PPARD (0.42) | PPARDTAAR1PIK3CAMTORRCE1 | |
| SCHEMBL6232652 | 0.77 | TAAR1 (0.41) | PPARDTAAR1RCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | PPARD 1747/4885TAAR1 1264/4885PIK3CA 3495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.