Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 12/20 | 0.72 |
| ▸ | ADRB3 | P13945 | 12/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6539290 | 0.88 | ADRB3 (0.79) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL7044140 | 0.85 | ADRB3 (0.73) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL6478914 | 0.83 | ADRB3 (0.71) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL7041021 | 0.83 | ADRB3 (0.71) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL6478911 | 0.83 | ADRB3 (0.71) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL6540041 | 0.83 | ADRB1 (0.68) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL7041978 | 0.83 | ADRB3 (0.74) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL7044333 | 0.83 | ADRB3 (0.71) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL7039822 | 0.83 | ADRB3 (0.74) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL6493585 | 0.83 | ADRB3 (0.59) | ADRB1ADRB3MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |
| WO-2002024635-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-28 | — | — | WO | disclosed |