Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539970 | 0.94 | GAA (0.51) | GAAALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7039646 | 0.88 | KMT2A (0.40) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7037102 | 0.87 | MAPT (0.39) | GAAALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL6539034 | 0.85 | MAOB (0.48) | GAAALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7244637 | 0.84 | CTSV (0.41) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7040318 | 0.84 | CTSV (0.40) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7044399 | 0.84 | CTSV (0.40) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7042572 | 0.82 | KMT2A (0.44) | ALDH1A1SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL6478257 | 0.82 | POLB (0.50) | GAAALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7173615 | 0.82 | AR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |
| WO-2002024635-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-28 | — | — | WO | disclosed |