Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 16/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 16/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539058 | 0.90 | ADRB1 (0.45) | ADRB1ADRB3ADRB2MAPT | |
| SCHEMBL6538847 | 0.86 | ADRB1 (0.48) | ADRB1ADRB3ADRB2MAPTMEN1 | |
| SCHEMBL6539431 | 0.85 | NPC1 (0.45) | ADRB1ADRB3ADRB2MAPTMEN1 | |
| SCHEMBL6538698 | 0.82 | NPC1 (0.43) | ADRB1ADRB3ADRB2MAPTNPC1 | |
| SCHEMBL6539710 | 0.82 | ADRB1 (0.53) | ADRB1ADRB3ADRB2MAPTMEN1 | |
| SCHEMBL6539510 | 0.82 | ADRB1 (0.59) | ADRB1ADRB3ADRB2MAPT | |
| SCHEMBL6538911 | 0.81 | ADRB3 (0.56) | ADRB1ADRB3ADRB2MAPTMEN1 | |
| SCHEMBL6538627 | 0.81 | ADRB3 (0.72) | ADRB1ADRB3ADRB2MAPT | |
| SCHEMBL6539311 | 0.81 | ADRB1 (0.45) | ADRB1ADRB3ADRB2MAPTMEN1 | |
| SCHEMBL6539444 | 0.79 | KMT2A (0.52) | ADRB1ADRB3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |