Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 11/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539647 | 1.00 | ADRB3 (0.48) | ADRB3ADRB1CYP3A4CYP2D6USP2 | |
| SCHEMBL6553106 | 0.90 | ADRB3 (0.61) | ADRB3ADRB1CYP3A4CYP2D6USP2 | |
| SCHEMBL6553102 | 0.90 | ADRB3 (0.61) | ADRB3ADRB1CYP3A4CYP2D6USP2 | |
| SCHEMBL6541299 | 0.89 | ADRB3 (0.60) | ADRB3ADRB1CYP3A4CYP2D6USP2 | |
| SCHEMBL6541292 | 0.89 | ADRB3 (0.50) | ADRB3ADRB1CYP3A4CYP2D6USP2 | |
| SCHEMBL6539716 | 0.87 | ADRB3 (0.65) | ADRB3ADRB1CYP3A4CYP2D6ADRA1A | |
| SCHEMBL6553139 | 0.87 | ADRB3 (0.65) | ADRB3ADRB1CYP3A4CYP2D6ADRA1A | |
| SCHEMBL6553136 | 0.87 | ADRB3 (0.65) | ADRB3ADRB1CYP3A4CYP2D6ADRA1A | |
| SCHEMBL6539713 | 0.87 | ADRB3 (0.65) | ADRB3ADRB1CYP3A4CYP2D6ADRA1A | |
| SCHEMBL10773274 | 0.87 | ADRB1 (0.60) | ADRB3ADRB1CYP3A4CYP2D6USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | ADRB3 58/4885ADRB1 7/4885CYP3A4 4197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.