Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 10/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538879 | 0.87 | CA12 (0.43) | SUCNR1PPARDCA12CA1CA2 | |
| SCHEMBL6539653 | 0.84 | PPARD (0.51) | PPARD | |
| SCHEMBL6539696 | 0.83 | PPARD (0.47) | PPARD | |
| SCHEMBL6539658 | 0.83 | PPARD (0.47) | PPARD | |
| SCHEMBL6540393 | 0.83 | SUCNR1 (0.47) | SUCNR1CA12CA1CA2CA9 | |
| SCHEMBL6232465 | 0.83 | SUCNR1 (0.47) | SUCNR1CA12CA1CA2CA9 | |
| SCHEMBL6539861 | 0.80 | PPARD (0.55) | PPARD | |
| SCHEMBL6538946 | 0.79 | PPARD (0.56) | PPARD | |
| SCHEMBL6538965 | 0.78 | HDAC8 (0.45) | PPARD | |
| SCHEMBL21601467 | 0.78 | CA12 (0.69) | SUCNR1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | SUCNR1 233/4885PPARD 1747/4885CA12 3116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.