Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 10/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 10/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538732 | 0.91 | ADRB1 (0.50) | ADRB1ADRB3ADRB2MEN1KMT2A | |
| SCHEMBL6538563 | 0.91 | ADRB1 (0.54) | ADRB1ADRB3ADRB2MEN1KMT2A | |
| SCHEMBL6540060 | 0.91 | ADRB1 (0.48) | ADRB1ADRB3ADRB2MEN1KMT2A | |
| SCHEMBL6539381 | 0.90 | ADRB1 (0.54) | ADRB1ADRB3ADRB2MEN1KMT2A | |
| SCHEMBL6538889 | 0.90 | ADRB1 (0.49) | ADRB1ADRB3ADRB2MEN1KMT2A | |
| SCHEMBL6538485 | 0.89 | ADRB1 (0.47) | ADRB1ADRB3ADRB2MEN1KMT2A | |
| SCHEMBL6538663 | 0.89 | ADRB1 (0.48) | ADRB1ADRB3ADRB2MEN1KMT2A | |
| SCHEMBL6538597 | 0.86 | NR1H4 (0.48) | ADRB1ADRB3ADRB2MEN1KMT2A | |
| SCHEMBL6539510 | 0.86 | ADRB1 (0.59) | ADRB1ADRB3ADRB2MAPT | |
| SCHEMBL6539617 | 0.85 | ADRB1 (0.57) | ADRB1ADRB3ADRB2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |