Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 4/20 | 0.34 |
| ▸ | ACHE | P22303 | 4/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539847 | 1.00 | PPARD (0.40) | PPARDRAB9AKCNH2KMT2AMEN1 | |
| SCHEMBL6207246 | 0.78 | PPARD (0.45) | PPARDKMT2AMEN1PPARGPPARA | |
| SCHEMBL6324977 | 0.78 | PPARD (0.42) | PPARDBCHEPPARGPPARATAAR1 | |
| SCHEMBL6539806 | 0.77 | PPARD (0.39) | PPARDBCHEPPARGPPARATAAR1 | |
| SCHEMBL6539657 | 0.75 | PPARD (0.43) | PPARDKMT2AMEN1PPARGPPARA | |
| SCHEMBL6208509 | 0.75 | PPARD (0.42) | PPARDKMT2AMEN1PPARGPPARA | |
| SCHEMBL6207227 | 0.75 | PPARD (0.44) | PPARDPPARGPPARATAAR1 | |
| Hydrochloric Acid SCHEMBL6538837 | 0.75 | PPARD (0.42) | PPARDKMT2AMEN1PPARGPPARA | |
| SCHEMBL6538983 | 0.74 | PPARD (0.43) | PPARDKMT2AMEN1TAAR1 | |
| SCHEMBL6324981 | 0.74 | PPARD (0.42) | PPARDPPARGPPARATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | PPARD 1747/4885RAB9A 4006/4885KCNH2 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.