Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 5/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540172 | 1.00 | ADRB1 (0.40) | ADRB1ADRB3TP53CYP51A1CA12 | |
| SCHEMBL6540148 | 0.92 | TP53 (0.43) | ADRB1ADRB3TP53CA12CA1 | |
| SCHEMBL6540137 | 0.92 | TP53 (0.43) | ADRB1ADRB3TP53CA12CA1 | |
| SCHEMBL6803249 | 0.92 | TP53 (0.40) | ADRB1ADRB3TP53CA12CA1 | |
| SCHEMBL6540304 | 0.91 | ADRB3 (0.49) | ADRB1ADRB3CA12CA1CA2 | |
| SCHEMBL6540308 | 0.91 | ADRB3 (0.49) | ADRB1ADRB3CA12CA1CA2 | |
| SCHEMBL6679253 | 0.90 | KDM4E (0.42) | TP53CA12CA1CA2CA4 | |
| SCHEMBL6679254 | 0.90 | KDM4E (0.42) | TP53CA12CA1CA2CA4 | |
| SCHEMBL6540284 | 0.89 | TP53 (0.52) | ADRB1ADRB3TP53POLBNPSR1 | |
| SCHEMBL6540279 | 0.89 | TP53 (0.52) | ADRB1ADRB3TP53POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | ADRB1 7/4885ADRB3 58/4885TP53 3788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.