Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.44 |
| ▸ | PPARD | Q03181 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6541275 | 0.88 | PTPN1 (0.47) | PTPN1PTGDR2KMT2AALDH1A1GAA | |
| SCHEMBL6539542 | 0.87 | TSHR (0.47) | ALDH1A1 | |
| SCHEMBL6541242 | 0.87 | CA1 (0.40) | ALDH1A1GAA | |
| SCHEMBL6554075 | 0.85 | KMT2A (0.45) | KMT2AALDH1A1GAA | |
| SCHEMBL6554072 | 0.84 | CA1 (0.40) | KMT2AALDH1A1GAA | |
| SCHEMBL6541355 | 0.82 | PTPN1 (0.46) | PTPN1APEX1PTGDR2PPARDKDM4E | |
| SCHEMBL6540265 | 0.82 | NAMPT (0.46) | ALDH1A1 | |
| SCHEMBL6540407 | 0.82 | CA1 (0.47) | ALDH1A1GAA | |
| SCHEMBL6677132 | 0.81 | HTT (0.42) | ALDH1A1GAA | |
| SCHEMBL6681831 | 0.81 | POLB (0.39) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | PTPN1 4443/4885APEX1 1313/4885PTGDR2 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.