Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554075 | 0.90 | KMT2A (0.45) | CA1CA2TSHRCA9CA12 | |
| SCHEMBL6539542 | 0.87 | TSHR (0.47) | CA1CA2TSHRCA9ALDH1A1 | |
| SCHEMBL6541242 | 0.84 | CA1 (0.40) | CA1CA2TSHRCA9CA12 | |
| SCHEMBL6540191 | 0.84 | PTPN1 (0.47) | KMT2AALDH1A1GAA | |
| SCHEMBL6553980 | 0.82 | ESR1 (0.40) | KMT2AGAA | |
| SCHEMBL6540407 | 0.82 | CA1 (0.47) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL6677132 | 0.81 | HTT (0.42) | ALDH1A1GAA | |
| SCHEMBL6677005 | 0.80 | TSHR (0.47) | CA1CA2TSHRCA9KMT2A | |
| SCHEMBL6540265 | 0.80 | NAMPT (0.46) | CA1CA2TSHRCA9CA12 | |
| SCHEMBL6677713 | 0.79 | CA1 (0.43) | CA1CA2TSHRCA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |