Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 5/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6228805 | 0.89 | MKNK1 (0.50) | RCE1PPARDTAAR1MKNK1MKNK2 | |
| SCHEMBL6539905 | 0.88 | RCE1 (0.46) | NR4A2RCE1PPARDTAAR1MKNK1 | |
| SCHEMBL6208143 | 0.87 | MEN1 (0.53) | NR4A2PPARDMEN1KMT2AATR | |
| SCHEMBL6235990 | 0.81 | PPARD (0.43) | NR4A2RCE1PPARDTAAR1MKNK1 | |
| SCHEMBL6208237 | 0.80 | MKNK1 (0.50) | NR4A2RCE1PPARDMKNK1MKNK2 | |
| SCHEMBL6539358 | 0.79 | RCE1 (0.46) | RCE1PPARDTAAR1MKNK1MKNK2 | |
| SCHEMBL6207562 | 0.79 | RCE1 (0.46) | RCE1PPARDTAAR1MKNK1MKNK2 | |
| SCHEMBL6538975 | 0.79 | PPARD (0.49) | RCE1PPARDTAAR1MEN1KMT2A | |
| SCHEMBL6539675 | 0.79 | MEN1 (0.51) | NR4A2PPARDMKNK1MKNK2MEN1 | |
| SCHEMBL6539085 | 0.78 | PPARD (0.54) | RCE1PPARDTAAR1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | NR4A2 883/4885RCE1 337/4885PPARD 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.