Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540289 | 0.77 | PPARD (0.34) | TSHR | |
| SCHEMBL30616079 | 0.74 | TSHR (0.52) | TSHR | |
| SCHEMBL22720593 | 0.74 | TSHR (0.61) | TSHR | |
| SCHEMBL35436 | 0.73 | — | — | |
| SCHEMBL3974885 | 0.73 | KMT2A (0.30) | TSHR | |
| SCHEMBL9891058 | 0.72 | TSHR (0.43) | TSHR | |
| SCHEMBL346640 | 0.70 | — | — | |
| SCHEMBL20539620 | 0.70 | — | — | |
| Methane SCHEMBL14562663 | 0.70 | — | — | |
| Ethane SCHEMBL1199897 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408980-A4 | NOVEL QUINAZOLINES AND USES THEREOF | ARIAD PHARMA INC (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-1408980-A2 | NOVEL QUINAZOLINES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003000188-A2 | NOVEL QUINAZOLINES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2003-01-03 | — | — | WO | disclosed |