Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28654029 | 0.86 | PPARD (0.34) | PPARDTSHR | |
| SCHEMBL6540293 | 0.77 | TSHR (0.44) | TSHR | |
| SCHEMBL2846018 | 0.75 | — | — | |
| SCHEMBL30616079 | 0.71 | TSHR (0.52) | PPARDTSHR | |
| Ethylene SCHEMBL27503872 | 0.71 | PPARD (0.31) | PPARD | |
| Methyl Alcohol SCHEMBL11431123 | 0.70 | ALDH1A1 (0.33) | — | |
| Ethyl Hydrogen Phosphonate SCHEMBL11598876 | 0.70 | KDM4E (0.36) | PPARDTSHR | |
| SCHEMBL3974885 | 0.69 | KMT2A (0.30) | TSHR | |
| SCHEMBL35436 | 0.69 | — | — | |
| Ethyl Hydrogen Phosphonate SCHEMBL5885178 | 0.69 | PPARD (0.36) | PPARDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408980-A4 | NOVEL QUINAZOLINES AND USES THEREOF | ARIAD PHARMA INC (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-1408980-A2 | NOVEL QUINAZOLINES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003000188-A2 | NOVEL QUINAZOLINES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2003-01-03 | — | — | WO | disclosed |