Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5152241 | 0.91 | PTGS1 (0.49) | PTGS2PTGS1FABP3FABP4MALT1 | |
| SCHEMBL5148721 | 0.84 | PTGS2 (0.60) | PTGS2PTGS1FABP3FABP4MALT1 | |
| SCHEMBL5147704 | 0.83 | CCKAR (0.49) | PTGS2PTGS1FABP3FABP4MALT1 | |
| SCHEMBL5152133 | 0.82 | PTGS2 (0.39) | PTGS2PTGS1FABP3FABP4MALT1 | |
| SCHEMBL14504708 | 0.81 | — | — | |
| SCHEMBL5147883 | 0.80 | MALT1 (0.47) | PTGS2PTGS1FABP3FABP4MALT1 | |
| SCHEMBL5152203 | 0.80 | MALT1 (0.47) | PTGS2PTGS1FABP3FABP4MALT1 | |
| SCHEMBL14504707 | 0.80 | RPA1 (0.50) | PTGS2PTGS1MALT1CHRNA7 | |
| SCHEMBL5148977 | 0.80 | BCL2 (0.43) | FABP3FABP4MALT1CHRNA7 | |
| SCHEMBL5147814 | 0.79 | MALT1 (0.51) | PTGS2PTGS1FABP3FABP4MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116475-A1 | Pyrazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-17 | — | — | US | disclosed |