Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199957 | 1.00 | FFAR1 (0.39) | FFAR1KMT2AKDM4EALDH1A1DCUN1D1 | |
| SCHEMBL7199952 | 1.00 | FFAR1 (0.39) | FFAR1KMT2AKDM4EALDH1A1DCUN1D1 | |
| SCHEMBL6540421 | 0.90 | FFAR1 (0.47) | FFAR1 | |
| SCHEMBL6541058 | 0.89 | FFAR1 (0.44) | FFAR1KMT2ADCUN1D1 | |
| SCHEMBL7200082 | 0.89 | FFAR1 (0.44) | FFAR1KMT2ADCUN1D1 | |
| SCHEMBL7200079 | 0.89 | FFAR1 (0.44) | FFAR1KMT2ADCUN1D1 | |
| Hydrochloric Acid SCHEMBL6540472 | 0.86 | TACR1 (0.47) | FFAR1KMT2A | |
| SCHEMBL6541644 | 0.84 | TACR1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL6541085 | 0.82 | KDM4E (0.51) | KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7201320 | 0.81 | TACR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787543-B2 | PREPARATION OF TACHYKININ ANTAGONISTS; SUBSTITUTED NITROGEN-CONTAINING HETEROCYCLES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| US-20030176430-A1 | Benzhydryl derivatives | ASTELLAS PHARMA INC. (JP) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176430-A1 | Benzhydryl derivatives | BDKRB1, BDKRB2, TACR1 | FFAR1 980/4885KMT2A 2124/4885KDM4E 3697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.