Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 9/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2168184 | 1.00 | CCR5 (0.43) | CCR5ALDH1A1RAB9AHPGDLRRK2 | |
| SCHEMBL1355279 | 0.85 | HTT (0.50) | CCR5ALDH1A1RAB9AHPGDLRRK2 | |
| Racephedrine SCHEMBL2168767 | 0.83 | CCR5 (0.44) | CCR5ALDH1A1RAB9AHPGDLRRK2 | |
| Racephedrine SCHEMBL2168179 | 0.83 | CCR5 (0.44) | CCR5ALDH1A1RAB9AHPGDLRRK2 | |
| SCHEMBL724611 | 0.81 | NPSR1 (0.46) | CCR5ALDH1A1RAB9ALRRK2HTT | |
| SCHEMBL12293726 | 0.80 | CCR5 (0.47) | CCR5ALDH1A1RAB9AHPGDLRRK2 | |
| SCHEMBL2167632 | 0.80 | KMT2A (0.47) | CCR5ALDH1A1RAB9AHPGDLRRK2 | |
| SCHEMBL1783943 | 0.80 | KMT2A (0.47) | CCR5ALDH1A1RAB9AHPGDLRRK2 | |
| SCHEMBL2166135 | 0.80 | KMT2A (0.47) | CCR5ALDH1A1RAB9AHPGDLRRK2 | |
| SCHEMBL9287833 | 0.79 | HTT (0.46) | CCR5ALDH1A1RAB9AHPGDLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713464-B1 | ANTIMUSCARINIC AGENTS WITH SUPERIOR PHARMACOKINETICS | SCHWARZ PHARMA AG (DE) | 2004-03-30 | — | — | US | disclosed |