Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 6/20 | 0.40 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA4 | P22748 | 6/20 | 0.40 |
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | PTGIR | P43119 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540661 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KCNH2CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL6541337 | 0.86 | MAPT (0.42) | ALDH1A1KCNH2CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL6541341 | 0.86 | MAPT (0.42) | ALDH1A1KCNH2CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL6540725 | 0.85 | ADRB3 (0.53) | ALDH1A1KCNH2CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL6540720 | 0.85 | ADRB3 (0.53) | ALDH1A1KCNH2CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL6540723 | 0.85 | ADRB3 (0.53) | ALDH1A1KCNH2CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL6540107 | 0.81 | ADRB3 (0.52) | ALDH1A1CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6540102 | 0.81 | ADRB3 (0.52) | ALDH1A1CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6271201 | 0.81 | KMT2A (0.38) | ALDH1A1KCNH2CYP2C9CA12CA1 | |
| SCHEMBL6271198 | 0.81 | KMT2A (0.38) | ALDH1A1KCNH2CYP2C9CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | ALDH1A1 188/4885KCNH2 211/4885CYP2C9 3959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.