Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 12/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540711 | 1.00 | ADRB3 (0.42) | ADRB3ADRB1KCNH2PSEN1PSEN2 | |
| SCHEMBL6267975 | 0.89 | PTPN2 (0.40) | ADRB3ADRB1KCNH2L3MBTL1 | |
| SCHEMBL6267977 | 0.89 | PTPN2 (0.40) | ADRB3ADRB1KCNH2L3MBTL1 | |
| SCHEMBL6540148 | 0.86 | TP53 (0.43) | ADRB3ADRB1KCNH2TAS2R14 | |
| SCHEMBL6540137 | 0.86 | TP53 (0.43) | ADRB3ADRB1KCNH2TAS2R14 | |
| SCHEMBL6803249 | 0.86 | TP53 (0.40) | ADRB3ADRB1KCNH2L3MBTL1 | |
| SCHEMBL6678776 | 0.86 | ADRB3 (0.43) | ADRB3ADRB1PSEN1PSEN2SPPL2A | |
| SCHEMBL6540308 | 0.86 | ADRB3 (0.49) | ADRB3ADRB1PSEN1PSEN2SPPL2A | |
| SCHEMBL6540304 | 0.86 | ADRB3 (0.49) | ADRB3ADRB1PSEN1PSEN2SPPL2A | |
| SCHEMBL6678773 | 0.86 | ADRB3 (0.43) | ADRB3ADRB1PSEN1PSEN2SPPL2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | ADRB3 58/4885ADRB1 7/4885KCNH2 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.