Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540712 | 1.00 | TP53 (0.51) | TP53POLBMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL6806332 | 0.90 | TP53 (0.41) | TP53POLBMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL6676696 | 0.90 | TP53 (0.41) | TP53POLBMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL6540591 | 0.89 | MAPT (0.49) | TP53POLBMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL6540594 | 0.89 | MAPT (0.49) | TP53POLBMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL6540765 | 0.88 | TP53 (0.56) | TP53POLBMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL6540772 | 0.88 | TP53 (0.56) | TP53POLBMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL6540702 | 0.88 | POLB (0.44) | TP53POLBMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL6540697 | 0.88 | POLB (0.44) | TP53POLBMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL10812044 | 0.85 | ADRB3 (0.52) | ADRB3ADRB1ADRB2CYP2D6ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | TP53 3788/4885POLB 1231/4885MAPT 4502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.