Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 10/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806332 | 1.00 | TP53 (0.41) | TP53ADRB3ADRB1ADRB2CYP2D6 | |
| SCHEMBL6540712 | 0.90 | TP53 (0.51) | TP53ADRB3ADRB1ADRB2CYP2D6 | |
| SCHEMBL6540707 | 0.90 | TP53 (0.51) | TP53ADRB3ADRB1ADRB2CYP2D6 | |
| SCHEMBL6681059 | 0.85 | PSEN1 (0.40) | ADRB3ADRB1ADRB2CYP2D6ADRA1D | |
| SCHEMBL6681061 | 0.85 | PSEN1 (0.40) | ADRB3ADRB1ADRB2CYP2D6ADRA1D | |
| SCHEMBL6683514 | 0.83 | ADRB3 (0.46) | ADRB3ADRB1ADRB2CYP2D6ADRA1D | |
| SCHEMBL6683518 | 0.83 | ADRB3 (0.46) | ADRB3ADRB1ADRB2CYP2D6ADRA1D | |
| SCHEMBL6680461 | 0.81 | ADRB3 (0.57) | ADRB3ADRB1ADRB2CYP2D6ADRA1D | |
| SCHEMBL6680463 | 0.81 | ADRB3 (0.57) | ADRB3ADRB1ADRB2CYP2D6ADRA1D | |
| SCHEMBL6804791 | 0.81 | CNR2 (0.38) | ADRB3ADRB1ADRB2CYP2D6ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FANCD2, FANCI, HRH2 | TP53 3318/4885ADRB3 150/4885ADRB1 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.