Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.45 |
| ▸ | AKT1 | P31749 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823156 | 0.92 | HDAC1 (0.54) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL3695642 | 0.88 | HDAC1 (0.55) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL1798901 | 0.88 | HDAC1 (0.52) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL580233 | 0.88 | HDAC1 (0.55) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL13708399 | 0.87 | HDAC1 (0.52) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL13617803 | 0.87 | HDAC1 (0.52) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL2595460 | 0.87 | HDAC1 (0.51) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL27540555 | 0.87 | HDAC1 (0.51) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| Water SCHEMBL28757509 | 0.86 | HDAC1 (0.50) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL1797681 | 0.86 | HDAC1 (0.50) | HDAC1HDAC3HDAC2NCOR2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
| US-20040106653-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | HDAC1 1603/4885HDAC3 2501/4885HDAC2 968/4885 |
| US-20040106653-A1 | Aminoalcohol derivatives | FANCD2, FANCI, HRH2 | HDAC1 3164/4885HDAC3 3039/4885HDAC2 2822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.