Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 12/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 12/20 | 0.48 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6541405 | 0.88 | LPAR1 (0.54) | LPAR1LPAR5HDAC1HDAC3HDAC2 | |
| SCHEMBL6802456 | 0.86 | LPAR1 (0.47) | LPAR1LPAR5HDAC1HDAC3HDAC2 | |
| SCHEMBL6539902 | 0.85 | HDAC1 (0.49) | LPAR1LPAR5HDAC1HDAC3HDAC2 | |
| SCHEMBL6539899 | 0.85 | RCE1 (0.42) | LPAR1LPAR5HDAC1HDAC3HDAC2 | |
| SCHEMBL6810353 | 0.84 | HDAC1 (0.46) | LPAR1LPAR5HDAC1HDAC3HDAC2 | |
| SCHEMBL6677473 | 0.84 | LPAR1 (0.60) | LPAR1LPAR5HDAC1HDAC3HDAC2 | |
| SCHEMBL579680 | 0.83 | LPAR1 (0.54) | LPAR1LPAR5HDAC1HDAC3HDAC2 | |
| SCHEMBL6679747 | 0.81 | LPAR1 (0.52) | LPAR1LPAR5HDAC1HDAC3HDAC2 | |
| SCHEMBL9823156 | 0.81 | HDAC1 (0.54) | LPAR1LPAR5HDAC1HDAC3HDAC2 | |
| SCHEMBL6800067 | 0.81 | LPAR1 (0.49) | LPAR1LPAR5HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | LPAR1 362/4885LPAR5 719/4885MMP2 4321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.