Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 12/20 | 0.52 |
| ▸ | LPAR5 | Q9H1C0 | 9/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677473 | 0.94 | LPAR1 (0.60) | LPAR1LPAR5HDAC1HDAC3HDAC2 | |
| SCHEMBL6806805 | 0.91 | LPAR1 (0.44) | LPAR1LPAR5HDAC1HDAC3HDAC2 | |
| SCHEMBL6800067 | 0.87 | LPAR1 (0.49) | LPAR1LPAR5HDAC1HDAC3HDAC2 | |
| SCHEMBL6540212 | 0.84 | LPAR1 (0.39) | LPAR1LPAR5HDAC1HDAC3HDAC2 | |
| SCHEMBL6677130 | 0.83 | LPAR1 (0.51) | LPAR1LPAR5HDAC1HDAC3HDAC2 | |
| SCHEMBL6540326 | 0.83 | HDAC1 (0.43) | LPAR1LPAR5HDAC1HDAC3HDAC2 | |
| SCHEMBL6539875 | 0.82 | PPARA (0.48) | LPAR1LPAR5HDAC1HDAC3HDAC2 | |
| SCHEMBL6540935 | 0.81 | LPAR1 (0.48) | LPAR1LPAR5HDAC1HDAC3HDAC2 | |
| SCHEMBL6541405 | 0.81 | LPAR1 (0.54) | LPAR1LPAR5HDAC1HDAC3HDAC2 | |
| SCHEMBL6539902 | 0.81 | HDAC1 (0.49) | LPAR1LPAR5HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |