Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680430 | 0.94 | ALK (0.47) | NLRP3NAMPTKMT2A | |
| SCHEMBL6544777 | 0.88 | NAMPT (0.48) | NLRP3NAMPTTSHR | |
| SCHEMBL6541135 | 0.88 | TSHR (0.50) | NLRP3ALDH1A1TSHR | |
| SCHEMBL6539542 | 0.88 | TSHR (0.47) | NLRP3ALDH1A1TSHR | |
| SCHEMBL6541199 | 0.87 | CA1 (0.40) | NLRP3ALDH1A1 | |
| SCHEMBL6541275 | 0.86 | PTPN1 (0.47) | ALDH1A1KMT2ATSHR | |
| SCHEMBL6540879 | 0.86 | USP2 (0.47) | NLRP3ALDH1A1TSHR | |
| SCHEMBL6677005 | 0.85 | TSHR (0.47) | NLRP3ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL6540929 | 0.84 | TSHR (0.47) | NLRP3ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL6810067 | 0.84 | HSD17B10 (0.46) | NLRP3ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | NLRP3 4535/4885ALDH1A1 188/4885NAMPT 4409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.