Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6541135 | 0.85 | TSHR (0.50) | HSD17B10ALDH1A1TSHRLMNANLRP3 | |
| SCHEMBL6539542 | 0.85 | TSHR (0.47) | ALDH1A1TSHRLMNANLRP3USP2 | |
| SCHEMBL6801180 | 0.85 | CA1 (0.45) | MEN1KMT2ACA1CA2CA7 | |
| SCHEMBL6544777 | 0.85 | NAMPT (0.48) | TSHRNLRP3USP2CA1CA2 | |
| SCHEMBL6541141 | 0.84 | NLRP3 (0.49) | ALDH1A1TSHRNLRP3MEN1KMT2A | |
| SCHEMBL6540929 | 0.84 | TSHR (0.47) | ALDH1A1TSHRSFRP1NLRP3MEN1 | |
| SCHEMBL6540091 | 0.84 | TSHR (0.47) | ALDH1A1TSHRSFRP1NLRP3MEN1 | |
| SCHEMBL6540879 | 0.83 | USP2 (0.47) | HSD17B10ALDH1A1TSHRLMNANLRP3 | |
| SCHEMBL6677005 | 0.82 | TSHR (0.47) | ALDH1A1TSHRNLRP3MEN1KMT2A | |
| SCHEMBL6539981 | 0.81 | MTNR1A (0.52) | ALDH1A1MEN1KMT2AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FANCD2, FANCI, HRH2 | HSD17B10 1189/4885ALDH1A1 168/4885TSHR 4442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.