SCHEMBL6541395

SCHEMBL6541395

CCOC(=O)C1CCCCN1C(N)=O

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 9/20 0.62
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 5/20 0.47
ALDH1A1 P00352 5/20 0.45
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
RECQL P46063 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7310339 0.98 FKBP1A (0.60) FKBP1AMEN1KMT2AKDM4EALDH1A1
SCHEMBL7304571 0.95 FKBP1A (0.56) FKBP1AMEN1KMT2AKDM4EALDH1A1
SCHEMBL496388 0.95 FKBP1A (0.56) FKBP1AMEN1KMT2AKDM4EALDH1A1
SCHEMBL25658114 0.95 FKBP1A (0.56) FKBP1AMEN1KMT2AKDM4EALDH1A1
Hydrochloric Acid SCHEMBL11660822 0.94 FKBP1A (0.55) FKBP1AMEN1KMT2AKDM4EALDH1A1
SCHEMBL24661351 0.87 FKBP1A (0.65) FKBP1AMEN1KMT2AKDM4EALDH1A1
SCHEMBL5485208 0.85 FKBP1A (0.63) FKBP1AMEN1KMT2AKDM4EALDH1A1
SCHEMBL395832 0.85 FKBP1A (0.63) FKBP1AMEN1KMT2AKDM4EALDH1A1
SCHEMBL13373975 0.85 FKBP1A (0.63) FKBP1AMEN1KMT2AKDM4EALDH1A1
SCHEMBL5833327 0.83 FKBP1A (0.68) FKBP1AMEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0588655-B1 Amidinophenol derivatives ONO PHARMACEUTICAL CO (JP) 1996-12-04 EP claimed
EP-1361876-A4 NOVEL CANNABIMIMETIC LIGANDS UNIV CONNECTICUT (US) 2004-03-31 EP disclosed
EP-1361876-A2 NOVEL CANNABIMIMETIC LIGANDS The University of Connecticut (US) 2003-11-19 EP disclosed
WO-2002058636-A2 NOVEL CANNABIMIMETIC LIGANDS UNIVERSITY OF CONNECTICUT (US) 2002-08-01 WO disclosed