Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540140 | 0.91 | SMN1; SMN2 (0.46) | SMN1; SMN2TP53MAPTALDH1A1NPSR1 | |
| SCHEMBL6541100 | 0.88 | SMN1; SMN2 (0.68) | SMN1; SMN2TP53MAPTALDH1A1NPSR1 | |
| SCHEMBL6540593 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2TP53MAPTALDH1A1NPSR1 | |
| SCHEMBL6540180 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2TP53MAPTALDH1A1NPSR1 | |
| SCHEMBL6540975 | 0.83 | MAPT (0.44) | SMN1; SMN2TP53MAPTALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL6540354 | 0.82 | ADRB3 (0.65) | ADRB1ADRB3 | |
| SCHEMBL6679601 | 0.82 | CA2 (0.48) | SMN1; SMN2MAPTALDH1A1NPSR1ABL1 | |
| SCHEMBL6541404 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2TP53MAPTALDH1A1NPSR1 | |
| SCHEMBL6680443 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTALDH1A1NPSR1ABL1 | |
| SCHEMBL6539474 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2TP53MAPTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | SMN1; SMN2 2146/4885TP53 3788/4885MAPT 4502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.