Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.30 |
| ▸ | CRHBP | P24387 | 2/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34344 | 0.92 | — | — | |
| SCHEMBL16197636 | 0.92 | LMNA (0.47) | ALDH1A1LMNATP53TSHRCA1 | |
| SCHEMBL28379193 | 0.89 | CA1 (0.50) | ALDH1A1LMNATP53TSHRCA1 | |
| SCHEMBL31492941 | 0.89 | CA1 (0.50) | ALDH1A1LMNATP53TSHRCA1 | |
| SCHEMBL28886215 | 0.89 | CA1 (0.50) | ALDH1A1LMNATP53TSHRCA1 | |
| SCHEMBL3093303 | 0.89 | CA1 (0.50) | ALDH1A1LMNATP53TSHRCA1 | |
| SCHEMBL17672300 | 0.89 | CA1 (0.50) | ALDH1A1LMNATP53TSHRCA1 | |
| SCHEMBL4302406 | 0.89 | CA1 (0.50) | ALDH1A1LMNATP53TSHRCA1 | |
| SCHEMBL493682 | 0.89 | CA1 (0.50) | ALDH1A1LMNATP53TSHRCA1 | |
| SCHEMBL9788227 | 0.89 | CA1 (0.50) | ALDH1A1LMNATP53TSHRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1148847-A4 | COMPOSITE BONE GRAFT, METHOD OF MAKING AND USING SAME | LIFENET (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-1148847-A1 | COMPOSITE BONE GRAFT, METHOD OF MAKING AND USING SAME | Lifenet (US) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000040177-A1 | COMPOSITE BONE GRAFT, METHOD OF MAKING AND USING SAME | LIFENET (US) | 2000-07-13 | — | — | WO | disclosed |