SCHEMBL6542933

SCHEMBL6542933

C=CCc1n[nH]c(N)c1C#N

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PRKACA P17612 1/20 0.40
PRKACG P22612 1/20 0.40
PRKACB P22694 1/20 0.40
ALOX15 P16050 2/20 0.36
HSD17B10 Q99714 2/20 0.36
KDM4E B2RXH2 3/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
GAA P10253 1/20 0.31
GFER P55789 1/20 0.31
PLA2G2A P14555 1/20 0.31
CDK5 Q00535 1/20 0.31
DYRK1A Q13627 1/20 0.31
CDK5R1 Q15078 1/20 0.31
POLB P06746 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2876157 0.77 PRKACA (0.44) PRKACAPRKACGPRKACBKDM4EALDH1A1
SCHEMBL7029444 0.76 ALOX15 (0.33) ALOX15HSD17B10KDM4EALDH1A1MAPT
SCHEMBL31278209 0.76 PRKACA (0.43) PRKACAPRKACGPRKACBKDM4EGAA
SCHEMBL15202449 0.75 NPSR1 (0.30)
SCHEMBL13066533 0.74 KDM4E (0.46) PRKACAPRKACGPRKACBKDM4EGAA
SCHEMBL4931757 0.73 MAPK1 (0.50) PRKACAPRKACGPRKACBHSD17B10KDM4E
SCHEMBL31277953 0.71 KDM4E (0.41) PRKACAPRKACGPRKACBALOX15HSD17B10
SCHEMBL4758500 0.70 MAPK1 (0.41) PRKACAPRKACGPRKACBKDM4EALDH1A1
SCHEMBL6249863 0.69 MAPT (0.47) PRKACAPRKACGPRKACBHSD17B10KDM4E
SCHEMBL8916628 0.68 PARP1 (0.44) PRKACAPRKACGPRKACBKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0492444-B1 Novel synthesis of pyrazole dyes EASTMAN KODAK CO (US) 1996-11-27 EP claimed
US-5144015-A Diazotization, salt formation, coupling, and alkylation to form 1-alkyl-3-alkyl or aryl-4-cyanopyrazol-5-yl azo dye EASTMAN KODAK COMPANY (US) 1992-09-01 US claimed
EP-0492444-A1 Novel synthesis of pyrazole dyes EASTMAN KODAK COMPANY (US) 1992-07-01 EP claimed
US-6682590-B2 IMAGE FASTNESS AND STABILITY FUJI PHOTO FILM CO., LTD. (JP) 2004-01-27 US disclosed
EP-1377640-A2 AZO COMPOUNDS AND PROCESS OF PRODUCING THE SAME AND NOVEL INTERMEDIATE COMPOUNDS USED IN THE PROCESS OF PRODUCING AZO COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 2004-01-07 EP disclosed
US-6613888-B2 Having good hue and capable of forming images having high lightfastness FUJI PHOTO FILM CO., LTD. (JP) 2003-09-02 US disclosed
US-20030040608-A1 Azo dyes, process for making the same, ink-jet printing ink, ink-jet recording method FUJIFILM CORPORATION (JP) 2003-02-27 US disclosed
US-6489452-B1 AN AZO DYE REPRESENTED BY THE FOLLOWING GENERAL FORMULA (1) AND A PROCESS FOR MAKING THE AZO DYE IS DISCLOSED. THE PROCESS COMPRISES A STEP IN WHICH A DIAZONIUM SALT IS FORMED BY THE REACTION BETWEEN AN AMINOPYRAZOLE AND AROMATIC COUPLING AGENT FUJI PHOTO FILM CO., LTD. (JP) 2002-12-03 US disclosed
WO-2002083662-A2 AZO COMPOUNDS AND PROCESS OF PRODUCING THE SAME AND NOVEL INTERMEDIATE COMPOUNDS USED IN THE PROCESS OF PRODUCING AZO COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 2002-10-24 WO disclosed
US-20020096082-A1 Ink composition for ink jet recording and image formation method FUJIFILM CORPORATION (JP) 2002-07-25 US disclosed
EP-0492444-B1 Novel synthesis of pyrazole dyes EASTMAN KODAK CO (US) 1996-11-27 EP disclosed
US-5144015-A Diazotization, salt formation, coupling, and alkylation to form 1-alkyl-3-alkyl or aryl-4-cyanopyrazol-5-yl azo dye EASTMAN KODAK COMPANY (US) 1992-09-01 US disclosed
US-5144015-A Diazotization, salt formation, coupling, and alkylation to form 1-alkyl-3-alkyl or aryl-4-cyanopyrazol-5-yl azo dye EASTMAN KODAK COMPANY (US) 1992-09-01 US disclosed
EP-0492444-A1 Novel synthesis of pyrazole dyes EASTMAN KODAK COMPANY (US) 1992-07-01 EP disclosed
EP-0492444-A1 Novel synthesis of pyrazole dyes EASTMAN KODAK COMPANY (US) 1992-07-01 EP disclosed