Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | PPARA | Q07869 | 6/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2438034 | 0.89 | PPARA (0.58) | PPARGPPARAPPARDMAPTKDM4E | |
| SCHEMBL7252733 | 0.88 | PPARG (0.47) | PPARGPPARAPPARDALDH1A1MAPT | |
| SCHEMBL6544141 | 0.88 | PPARA (0.56) | PPARGPPARAPPARDMAPTMTNR1A | |
| SCHEMBL6543066 | 0.87 | PPARA (0.57) | PPARGPPARAPPARDMAPTMTNR1A | |
| SCHEMBL6544080 | 0.87 | PPARA (0.57) | PPARGPPARAPPARDALDH1A1MAPT | |
| SCHEMBL6542915 | 0.87 | PPARA (0.57) | PPARGPPARAPPARDMAPTKDM4E | |
| SCHEMBL2440537 | 0.84 | PPARG (0.45) | PPARGPPARAPPARDALDH1A1MAPT | |
| SCHEMBL6543171 | 0.84 | PPARA (0.56) | PPARGPPARAPPARDALDH1A1MAPT | |
| SCHEMBL6543344 | 0.83 | PPARA (0.57) | PPARGPPARAPPARDALDH1A1MAPT | |
| SCHEMBL6544132 | 0.83 | PPARA (0.54) | PPARGPPARAPPARDMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |