Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.57 |
| ▸ | PPARG | P37231 | 13/20 | 0.57 |
| ▸ | PPARD | Q03181 | 4/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | FABP2 | P12104 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543171 | 0.97 | PPARA (0.56) | PPARAPPARGPPARDADRB3KDM4E | |
| SCHEMBL2438034 | 0.97 | PPARA (0.58) | PPARAPPARGPPARDADRB3KDM4E | |
| SCHEMBL6543344 | 0.96 | PPARA (0.57) | PPARAPPARGPPARDADRB3KDM4E | |
| SCHEMBL6542915 | 0.96 | PPARA (0.57) | PPARAPPARGPPARDADRB3KDM4E | |
| SCHEMBL6544141 | 0.95 | PPARA (0.56) | PPARAPPARGPPARDADRB3KDM4E | |
| SCHEMBL6543036 | 0.95 | PPARA (0.57) | PPARAPPARGPPARDADRB3KDM4E | |
| SCHEMBL6543066 | 0.94 | PPARA (0.57) | PPARAPPARGPPARDADRB3KDM4E | |
| SCHEMBL6544132 | 0.92 | PPARA (0.54) | PPARAPPARGPPARDADRB3KDM4E | |
| SCHEMBL6544109 | 0.90 | PPARG (0.59) | PPARAPPARGPPARDADRB3KDM4E | |
| SCHEMBL6544023 | 0.89 | PPARA (0.54) | PPARAPPARGPPARDADRB3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |