SCHEMBL6543071

SCHEMBL6543071

CC(C)(Oc1ccccc1CCCN(CCCc1ccccc1)c1nc2ccccc2o1)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 18/20 0.65
PPARG P37231 17/20 0.65
PPARD Q03181 12/20 0.65
FAAH O00519 1/20 0.43
CES1 P23141 1/20 0.43
DAGLA Q9Y4D2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6543498 0.97 PPARG (0.65) PPARAPPARGPPARDFAAHCES1
SCHEMBL6543916 0.92 PPARA (0.63) PPARAPPARGPPARD
SCHEMBL2469118 0.91 PPARG (0.71) PPARAPPARGPPARD
SCHEMBL14583509 0.89 PPARA (0.74) PPARAPPARGPPARD
SCHEMBL6544084 0.88 PPARA (0.58) PPARAPPARGPPARD
SCHEMBL6544117 0.87 PPARA (0.57) PPARAPPARGPPARD
SCHEMBL6543411 0.87 PPARG (0.64) PPARAPPARGPPARD
SCHEMBL6543006 0.87 PPARA (0.56) PPARAPPARGPPARD
SCHEMBL6542928 0.87 PPARG (0.74) PPARAPPARGPPARD
SCHEMBL6543936 0.86 PPARG (0.51) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1433786-A1 Benzoxazole compound and pharmaceutical composition containing the compound Kowa Company Ltd. (JP) 2004-06-30 EP disclosed
US-6653334-B1 Electively activate peroxisome proliferator activated receptors KOWA CO., LTD. (JP) 2003-11-25 US disclosed