Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.56 |
| ▸ | PPARG | P37231 | 16/20 | 0.56 |
| ▸ | PPARD | Q03181 | 14/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543017 | 0.95 | PPARA (0.55) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL6544104 | 0.92 | PPARA (0.54) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL6542906 | 0.88 | PPARA (0.67) | PPARAPPARGPPARD | |
| SCHEMBL6543916 | 0.87 | PPARA (0.63) | PPARAPPARGPPARD | |
| SCHEMBL6543071 | 0.87 | PPARA (0.65) | PPARAPPARGPPARD | |
| SCHEMBL6544084 | 0.87 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL6544277 | 0.86 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL6544117 | 0.86 | PPARA (0.57) | PPARAPPARGPPARD | |
| SCHEMBL2469118 | 0.85 | PPARG (0.71) | PPARAPPARGPPARDALDH1A1HSD17B10 | |
| SCHEMBL6544043 | 0.85 | PPARA (0.71) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |