Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 19/20 | 0.64 |
| ▸ | BRAF | P15056 | 19/20 | 0.64 |
| ▸ | JAK3 | P52333 | 1/20 | 0.57 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4040683 | 0.92 | JAK3 (0.54) | KITBRAFJAK3IRAK4 | |
| SCHEMBL6542947 | 0.88 | JAK3 (0.59) | KITBRAFJAK3IRAK4 | |
| SCHEMBL4034613 | 0.88 | JAK3 (0.52) | KITBRAFJAK3IRAK4 | |
| SCHEMBL6612511 | 0.87 | JAK3 (0.53) | KITBRAFJAK3IRAK4 | |
| SCHEMBL4042743 | 0.85 | KIT (0.53) | KITBRAF | |
| SCHEMBL4040691 | 0.84 | JAK3 (0.51) | KITBRAFJAK3IRAK4 | |
| SCHEMBL4034859 | 0.81 | IRAK4 (0.56) | KITBRAFJAK3IRAK4 | |
| SCHEMBL6542886 | 0.81 | JAK3 (0.51) | KITBRAFJAK3IRAK4 | |
| SCHEMBL4036359 | 0.80 | JAK3 (0.54) | KITBRAFJAK3IRAK4 | |
| SCHEMBL4032722 | 0.80 | KIT (0.50) | KITBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040254185-A1 | Selective anthranilamide pyridine amides as inhibitors of vegfr-2 and vegfr-3 | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254185-A1 | Selective anthranilamide pyridine amides as inhibitors of vegfr-2 and vegfr-3 | FLT4, KDR, FLT1 | KIT 34/4885BRAF 23/4885JAK3 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.