Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 1/20 | 0.51 |
| ▸ | CPA2 | P48052 | 1/20 | 0.51 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 7/20 | 0.50 |
| ▸ | F2 | P00734 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10956149 | 0.89 | F2 (0.48) | CPA1CPA2CPA4ACEF2 | |
| SCHEMBL6352076 | 0.88 | ACE (0.54) | CPA1CPA2CPA4ACEF2 | |
| Hydrochloric Acid SCHEMBL10974113 | 0.85 | DPP4 (0.56) | CPA1CPA2CPA4ACEF2 | |
| SCHEMBL20707067 | 0.84 | CYP3A4 (0.52) | ACEF2CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL31084237 | 0.83 | CTRB1 (0.69) | CTRB1ACE2 | |
| SCHEMBL9243269 | 0.83 | CTRB1 (0.69) | CTRB1ACE2 | |
| SCHEMBL9243277 | 0.83 | CTRB1 (0.69) | CTRB1ACE2 | |
| SCHEMBL6354335 | 0.82 | PSMB9 (0.51) | F2ITGB1ITGA4 | |
| SCHEMBL9334678 | 0.82 | PREP (0.60) | ACECTRB1CYP3A4CMA1 | |
| SCHEMBL9334682 | 0.82 | PREP (0.60) | ACECTRB1CYP3A4CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372620-A2 | METHODS FOR RESTORING COGNITIVE FUNCTION FOLLOWING SYSTEMIC STRESS | Saegis Pharmaceuticals (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002074293-A2 | METHODS FOR RESTORING COGNITIVE FUNCTION FOLLOWING SYSTEMIC STRESS | SAEGIS PHARMACEUTICALS INC (US) | 2002-09-26 | — | — | WO | disclosed |