Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.58 |
| ▸ | PPARG | P37231 | 5/20 | 0.58 |
| ▸ | FBP1 | P09467 | 9/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543550 | 0.89 | PPARA (0.45) | PPARAPPARGFBP1CYP3A4TSHR | |
| SCHEMBL6542904 | 0.87 | PPARG (0.53) | PPARAPPARG | |
| SCHEMBL6081371 | 0.84 | PPARA (0.61) | PPARAPPARGFBP1ABCB11CYP1A2 | |
| SCHEMBL6081046 | 0.82 | PPARA (0.67) | PPARAPPARGFBP1ABCB11CYP1A2 | |
| SCHEMBL6543477 | 0.81 | PPARA (0.66) | PPARAPPARGFBP1ABCB11CYP1A2 | |
| SCHEMBL21188241 | 0.79 | PPARA (0.67) | PPARAPPARGFBP1ABCB11CYP1A2 | |
| SCHEMBL6093013 | 0.79 | PPARA (0.70) | PPARAPPARGFBP1ABCB11CYP1A2 | |
| SCHEMBL14291406 | 0.78 | PPARA (0.69) | PPARAPPARGFBP1ABCB11CYP1A2 | |
| SCHEMBL1549446 | 0.78 | PPARA (0.69) | PPARAPPARGFBP1ABCB11CYP1A2 | |
| SCHEMBL6091395 | 0.78 | PPARA (0.69) | PPARAPPARGFBP1ABCB11CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |