Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.53 |
| ▸ | PPARA | Q07869 | 12/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6544041 | 0.87 | PPARA (0.58) | PPARGPPARA | |
| SCHEMBL6543550 | 0.87 | PPARA (0.45) | PPARGPPARA | |
| SCHEMBL5795465 | 0.84 | ALDH1A1 (0.56) | PPARGPPARACYP4F2CYP4A11PPARD | |
| SCHEMBL2434754 | 0.82 | ADRB2 (0.47) | PPARGPPARAPPARD | |
| SCHEMBL5795203 | 0.80 | PPARG (0.64) | PPARGPPARACYP4F2CYP4A11PPARD | |
| SCHEMBL7248386 | 0.78 | PPARG (0.61) | PPARGPPARACYP4F2CYP4A11PPARD | |
| SCHEMBL11215916 | 0.78 | PPARG (0.61) | PPARGPPARACYP4F2CYP4A11PPARD | |
| SCHEMBL31011750 | 0.76 | SRC (0.44) | — | |
| SCHEMBL203679 | 0.75 | ALDH1A1 (0.61) | — | |
| SCHEMBL27609022 | 0.75 | CYP3A4 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |