Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.59 |
| ▸ | PPARA | Q07869 | 9/20 | 0.59 |
| ▸ | PPARD | Q03181 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543898 | 0.97 | PPARG (0.58) | PPARGPPARAPPARDMAPTKDM4E | |
| SCHEMBL6544252 | 0.97 | PPARG (0.62) | PPARGPPARAPPARDMAPTRAB9A | |
| SCHEMBL6543114 | 0.96 | PPARG (0.57) | PPARGPPARAPPARDMAPTKDM4E | |
| SCHEMBL6544098 | 0.96 | PPARG (0.61) | PPARGPPARAPPARDMAPTRAB9A | |
| SCHEMBL6543404 | 0.95 | PPARG (0.60) | PPARGPPARAPPARDMAPTRAB9A | |
| SCHEMBL6543077 | 0.95 | PPARG (0.60) | PPARGPPARAPPARDMAPTKDM4E | |
| SCHEMBL6543021 | 0.95 | PPARG (0.59) | PPARGPPARAPPARDMAPTRAB9A | |
| SCHEMBL6542939 | 0.93 | PPARG (0.56) | PPARGPPARAPPARDMAPTRAB9A | |
| SCHEMBL6542943 | 0.90 | PPARA (0.56) | PPARGPPARAPPARDMAPTRAB9A | |
| SCHEMBL6544080 | 0.90 | PPARA (0.57) | PPARGPPARAPPARDMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |