Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542960 | 0.88 | TAAR1 (0.56) | TAAR1PPARAPPARGALDH1A1KDM4E | |
| SCHEMBL6543070 | 0.84 | POLB (0.55) | POLBRAB9ASMN1; SMN2 | |
| SCHEMBL6543060 | 0.77 | PPARA (0.54) | TAAR1PPARAPPARG | |
| SCHEMBL12204184 | 0.76 | ALDH1A1 (0.72) | TAAR1ALDH1A1KDM4ECTSLCTSS | |
| SCHEMBL2440291 | 0.76 | PPARA (0.59) | PPARAPPARG | |
| SCHEMBL2439051 | 0.76 | PPARA (0.53) | PPARAPPARGTDP1 | |
| SCHEMBL787022 | 0.75 | ALDH1A1 (0.74) | TAAR1ALDH1A1KDM4EPOLB | |
| SCHEMBL2438002 | 0.75 | PPARA (0.58) | TAAR1PPARAPPARG | |
| SCHEMBL6542699 | 0.74 | PPARA (0.44) | PPARAPPARGHPGD | |
| SCHEMBL1550516 | 0.73 | PPARA (0.49) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |