Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.59 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545160 | 1.00 | USP2 (0.62) | USP2HTTGPR84LPAR5CYP1A2 | |
| SCHEMBL6545195 | 1.00 | USP2 (0.62) | USP2HTTGPR84LPAR5CYP1A2 | |
| SCHEMBL6544651 | 1.00 | USP2 (0.62) | USP2HTTGPR84LPAR5CYP1A2 | |
| SCHEMBL6544849 | 1.00 | USP2 (0.62) | USP2HTTGPR84LPAR5CYP1A2 | |
| SCHEMBL6544523 | 1.00 | USP2 (0.62) | USP2HTTGPR84LPAR5CYP1A2 | |
| SCHEMBL4733804 | 0.93 | GPR84 (0.53) | USP2HTTGPR84LPAR5CYP1A2 | |
| SCHEMBL6803990 | 0.84 | GPR84 (0.68) | USP2HTTGPR84LPAR5CYP1A2 | |
| SCHEMBL6797869 | 0.84 | GPR84 (0.73) | USP2HTTGPR84LPAR5CYP1A2 | |
| SCHEMBL9628915 | 0.84 | USP2 (0.61) | USP2HTTGPR84LPAR5CYP1A2 | |
| SCHEMBL9628925 | 0.84 | USP2 (0.61) | USP2HTTGPR84LPAR5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931792-B1 | Depsipeptides containing non-natural amino acids | NISSHIN SEIFUN GROUP INC (JP) | 2004-01-07 | — | — | EP | disclosed |
| US-6288038-B1 | ACCELERATE APOLIPOPROTEIN E PRODUCTION; NERVOUS SYSTEM DISORDERS, ALZHEIMER*S DISEASE; ANTILIPEMIC AGENTS | NISSHIN SEIFUN GROUP INC. (JP) | 2001-09-11 | — | — | US | disclosed |
| EP-1028126-A1 | DEPSIPEPTIDE DERIVATIVES BEARING PIPERAZINONE RINGS | Nisshin Flour Milling Co., Ltd. (JP) | 2000-08-16 | — | — | EP | disclosed |
| EP-0931792-A1 | Depsipeptides containing non-natural amino acids | Nisshin Flour Milling Co., Ltd. (JP) | 1999-07-28 | — | — | EP | disclosed |