Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6544361 | 1.00 | ALDH1A1 (0.34) | ALDH1A1LMNALCKNPC1RAB9A | |
| SCHEMBL3243692 | 0.92 | ALDH1A1 (0.34) | ALDH1A1LMNALCKNPC1RAB9A | |
| SCHEMBL6544083 | 0.87 | MEN1 (0.42) | LMNANPC1RAB9AMAPTMEN1 | |
| SCHEMBL6544088 | 0.87 | MEN1 (0.42) | LMNANPC1RAB9AMAPTMEN1 | |
| SCHEMBL487505 | 0.82 | SMN1; SMN2 (0.40) | ALDH1A1LMNALCKNPC1RAB9A | |
| SCHEMBL3488698 | 0.81 | ALDH1A1 (0.43) | ALDH1A1LMNANPC1RAB9AMAPT | |
| SCHEMBL3244124 | 0.79 | MEN1 (0.42) | LMNANPC1RAB9AMAPTMEN1 | |
| SCHEMBL27939756 | 0.78 | KMT2A (0.39) | ALDH1A1LMNANPC1RAB9AMAPT | |
| SCHEMBL3487276 | 0.78 | TSHR (0.38) | ALDH1A1LMNANPC1RAB9AMAPT | |
| SCHEMBL3241737 | 0.78 | MEN1 (0.38) | ALDH1A1LMNANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1022272-B1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUNDS | SANKYO CO (JP) | 2004-05-26 | — | — | EP | disclosed |
| US-6432993-B1 | BENZIMIDAZOLE OR IMIDAZO(4,5-B)PYRIDINE DERIVATES; IMMUNOMODULATORS; ALDOSE REDUCTASE AND LIPOXYGENASE INHIBITORS; DIABETES; PREVENTS LIPID PEROXIDATION; ANTILIPEMIC, HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 2002-08-13 | — | — | US | disclosed |
| EP-1022272-A1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUNDS | Sankyo Company Limited (JP) | 2000-07-26 | — | — | EP | disclosed |