Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.85 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.85 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.85 |
| ▸ | LMNA | P02545 | 4/20 | 0.85 |
| ▸ | TSHR | P16473 | 3/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.85 |
| ▸ | SHBG | P04278 | 2/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.85 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.85 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.85 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.85 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.85 |
| ▸ | FNTA | P49354 | 5/20 | 0.78 |
| ▸ | FNTB | P49356 | 5/20 | 0.78 |
| ▸ | BLM | P54132 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | AR | P10275 | 1/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cortisone SCHEMBL10089738 | 0.92 | HSD17B10 (1.00) | HSD17B10NR3C1SERPINA6LMNATSHR | |
| Cortisone SCHEMBL13332835 | 0.92 | HSD17B10 (1.00) | HSD17B10NR3C1SERPINA6LMNATSHR | |
| Cortisone SCHEMBL13026135 | 0.92 | HSD17B10 (1.00) | HSD17B10NR3C1SERPINA6LMNATSHR | |
| Cortisone SCHEMBL6535496 | 0.92 | HSD17B10 (1.00) | HSD17B10NR3C1SERPINA6LMNATSHR | |
| Cortisone SCHEMBL9926754 | 0.92 | HSD17B10 (1.00) | HSD17B10NR3C1SERPINA6LMNATSHR | |
| Cortisone SCHEMBL4888 | 0.92 | HSD17B10 (1.00) | HSD17B10NR3C1SERPINA6LMNATSHR | |
| Cortisone SCHEMBL5082086 | 0.91 | HSD17B10 (0.98) | HSD17B10NR3C1SERPINA6LMNATSHR | |
| Cortisone SCHEMBL5082082 | 0.91 | HSD17B10 (0.98) | HSD17B10NR3C1SERPINA6LMNATSHR | |
| SCHEMBL16208665 | 0.91 | HSD17B10 (0.83) | HSD17B10NR3C1SERPINA6LMNATSHR | |
| Cortisone SCHEMBL28537808 | 0.91 | HSD17B10 (0.98) | HSD17B10NR3C1SERPINA6LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0954323-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A MIXTURE OF AUTOCROSS-LINKED HYALURONIC ACID AND NONAUTOCROSS-LINKED HYALURONIC ACID AND THEIR USE FOR THE TREATMENT OF ARTHROPATHIES | FIDIA SPA (IT) | 2004-01-07 | — | — | EP | disclosed |
| EP-0696598-B1 | Polysaccharide esters and their salts | FIDIA FARMACEUTICI (IT) | 2002-11-13 | — | — | EP | disclosed |
| US-6251876-B1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF ARTHROPATHIES COMPRISING AUTOCROSSLINKED HYALURONIC ACID, NONCROSSLINKED HYALURONIC ACID, PHARMACEUTICALLY ACCEPTABLE EXCIPIENT, DILUENT OR CARRIER | FIDIA, S.P.A. (IT) | 2001-06-26 | — | — | US | disclosed |
| EP-0614914-B1 | Crosslinked carboxy polysaccharides | FIDIA SPA (IT) | 2000-08-16 | — | — | EP | disclosed |
| EP-0954323-A1 | AUTOCROSS-LINKED HYALURONIC ACID AND RELATED PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ARTHROPATHIES | FIDIA S.p.A. (IT) | 1999-11-10 | — | — | EP | disclosed |
| EP-0648229-B1 | HYALURONIC ACID AND DERIVATIVES THEREOF IN INTERPENETRATING POLYMER NETWORKS (IPN) | MURST ITALIAN (IT) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997049412-A1 | AUTOCROSS-LINKED HYALURONIC ACID AND RELATED PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ARTHROPATHIES | FIDIA S.P.A. (IT) | 1997-12-31 | — | — | WO | disclosed |
| US-5676964-A | BIODEGRADABLE PLASTICS; MEDICAL EQUIPMENT; DISPOSABLE PRRODUCTS; COSMETICS; DRUGS; FOODS | FIDIA, S.P.A. (IT) | 1997-10-14 | — | — | US | disclosed |
| US-5644049-A | Biomaterial comprising hyaluronic acid and derivatives thereof in interpenetrating polymer networks (IPN) | M.U.R.S.T. ITALIAN MINISTRY FOR UNIVERSITITES AND SCIENTIFIC AND TECHNOLOGY RESEARCH (IT) | 1997-07-01 | — | — | US | disclosed |
| US-5506354-A | ANTIULCER, ANTITURMOR, ANTIARTHRITIC, ANTIATHEROSCLEROSIS, ANTIALLERGIC, ANTIASTHMA AGENTS | THE UPJOHN COMPANY (US) | 1996-04-09 | — | — | US | disclosed |
| US-5175281-A | Antiulcer, antiinflammatory, antiischemic, antiallergen, antisecretory, wound healing agents; cardiovascular disorders | THE UPJOHN COMPANY (US) | 1992-12-29 | — | — | US | disclosed |
| US-5099019-A | Central nervous system steroid derivative drugs | UPJOHN COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-4965353-A | ESTERS OF HYALURONIC ACID; MICROCAPSULES | FIDIA S.P.A. (IT) | 1990-10-23 | — | — | US | disclosed |
| WO-1989010941-A1 | CROSS-LINKED CARBOXY POLYSACCHARIDES | FIDIA S.P.A. (IT) | 1989-11-16 | — | — | WO | disclosed |
| EP-0341745-A1 | Crosslinked carboxy polysaccharides | FIDIA S.p.A. (IT) | 1989-11-15 | — | — | EP | disclosed |
| US-4851521-A | Esters of hyaluronic acid | FIDIA, S.P.A. (IT) | 1989-07-25 | — | — | US | disclosed |
| EP-0263213-A1 | C20 Through C26 amino steroids | THE UPJOHN COMPANY (US) | 1988-04-13 | — | — | EP | disclosed |
| EP-0238545-A1 | C 20? THROUGH C 26? AMINO STEROIDS. | UPJOHN CO (US) | 1987-09-30 | — | — | EP | disclosed |
| EP-0216453-A2 | Esters of hyaluronic acid and their salts. | FIDIA S.p.A. (IT) | 1987-04-01 | — | — | EP | disclosed |
| WO-1987001706-A2 | C20 THROUGH C26 AMINO STEROIDS | THE UPJOHN COMPANY (US) | 1987-03-26 | — | — | WO | disclosed |