Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.80 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.79 |
| ▸ | AR | P10275 | 4/20 | 0.79 |
| ▸ | PGR | P06401 | 5/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4178899 | 0.89 | NR3C1 (1.00) | NR3C1NR3C2ARPGR | |
| SCHEMBL4172146 | 0.89 | NR3C1 (0.84) | NR3C1NR3C2ARPGR | |
| SCHEMBL4182659 | 0.88 | NR3C1 (1.00) | NR3C1NR3C2ARPGR | |
| SCHEMBL4186071 | 0.87 | NR3C1 (0.82) | NR3C1NR3C2ARPGR | |
| SCHEMBL4181236 | 0.87 | NR3C1 (0.81) | NR3C1NR3C2ARPGR | |
| SCHEMBL4165850 | 0.87 | NR3C1 (0.81) | NR3C1NR3C2ARPGR | |
| SCHEMBL4182776 | 0.87 | NR3C1 (0.81) | NR3C1NR3C2ARPGR | |
| SCHEMBL6290314 | 0.86 | NR3C1 (0.75) | NR3C1NR3C2ARPGR | |
| SCHEMBL4176197 | 0.86 | NR3C1 (0.80) | NR3C1NR3C2ARPGR | |
| SCHEMBL4170528 | 0.86 | NR3C1 (0.80) | NR3C1NR3C2ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1375517-A1 | Structure of a glucocorticoid receptor ligand binding domain comprising an expanded binding pocket and methods employing same | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-02 | — | — | EP | disclosed |