Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.52 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5494693 | 0.88 | CYP3A4 (0.37) | LPAR3LPAR2LPAR1CYP3A4TRPM8 | |
| SCHEMBL5491381 | 0.83 | CYP3A4 (0.37) | LPAR3LPAR2LPAR1CYP3A4TRPM8 | |
| SCHEMBL2510789 | 0.82 | CYP3A4 (0.50) | LPAR3LPAR2LPAR1CYP3A4TRPM8 | |
| SCHEMBL31065565 | 0.81 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL27826149 | 0.81 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL31065561 | 0.81 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL27845150 | 0.81 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL27487571 | 0.81 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL11668416 | 0.81 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL575520 | 0.81 | TRPM8 (0.40) | LPAR3LPAR2LPAR1CYP3A4TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373280-A1 | PHOSPHONIUM PHOSPHINATE COMPOUNDS AND THEIR PREPARATION | Cytec Canada Inc. (CA) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002079212-A1 | PHOSPHONIUM PHOSPHINATE COMPOUNDS AND THEIR PREPARATION | CYTEC CANADA INC. (CA) | 2002-10-10 | — | — | WO | disclosed |