Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.34 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6398528 | 1.00 | BCHE (0.36) | BCHEALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL6398524 | 1.00 | BCHE (0.36) | BCHEALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL6403454 | 0.85 | KMT2A (0.42) | BCHEALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL6399556 | 0.83 | MEN1 (0.41) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6399561 | 0.83 | MEN1 (0.41) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6545132 | 0.83 | MEN1 (0.41) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6396697 | 0.80 | ALDH1A1 (0.39) | BCHEALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL6396693 | 0.80 | ALDH1A1 (0.39) | BCHEALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL6396690 | 0.80 | ALDH1A1 (0.39) | BCHEALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL6399154 | 0.78 | STS (0.38) | ALDH1A1SMN1; SMN2HTTKMT2APTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1375465-A9 | CYCLOOCTANONE DERIVATIVE AND CYCLODECANONE DERIVATIVE, AND USE THEREOF | Eisai Co., Ltd. (JP) | 2004-04-14 | — | — | EP | disclosed |
| EP-1375479-A1 | PYRROLIDINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | Eisai Co., Ltd. (JP) | 2004-01-02 | — | — | EP | disclosed |