SCHEMBL6544742

SCHEMBL6544742

O=C/C=C/C(=O)CC(=O)CC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.41
LDHA P00338 1/20 0.35
SRR Q9GZT4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleylacetoacetate SCHEMBL187863 0.76 TSHR (0.45) LDHASRR
Maleylacetoacetate SCHEMBL187565 0.76 TSHR (0.45) LDHASRR
Maleylacetoacetate SCHEMBL380205 0.76 TSHR (0.45) LDHASRR
SCHEMBL7745095 0.75 LDHA (0.42) LDHASRR
SCHEMBL6916408 0.74 LDHA (0.36) LDHASRR
SCHEMBL380204 0.71 LDHA (0.33) LDHASRR
SCHEMBL365997 0.71 LDHA (0.33) LDHASRR
SCHEMBL28522 0.71 LDHA (0.67) LDHASRR
SCHEMBL2184678 0.71 LDHA (0.67) LDHASRR
SCHEMBL7079440 0.70 LDHA (0.32) LDHASRR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1373533-A2 INCREASE IN THE VITAMIN E CONTENT IN ORGANISMS DUE TO AN INCREASE IN THE TYROSINE AMINOTRANSFERASE ACTIVITY Sungene GmbH & Co. KgAA (DE) 2004-01-02 EP claimed
WO-2002072848-A2 INCREASE IN THE VITAMIN E CONTENT IN ORGANISMS DUE TO AN INCREASE IN THE TYROSINE AMINOTRANSFERASE ACTIVITY SUNGENE GMBH & CO. KGAA (DE) 2002-09-19 WO claimed