Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.56 |
| ▸ | HSD17B3 | P37058 | 7/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | TACR2 | P21452 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10435794 | 1.00 | ESR1 (0.56) | ESR1ESR2HSD17B3ADRA2AADORA3 | |
| SCHEMBL5699266 | 0.92 | ESR1 (0.50) | ESR1ESR2HSD17B3ADRA2AADORA3 | |
| SCHEMBL5699297 | 0.92 | ESR1 (0.50) | ESR1ESR2HSD17B3ADRA2AADORA3 | |
| SCHEMBL28730305 | 0.92 | ESR1 (0.58) | ESR1ESR2HSD17B3ALDH1A1CYP3A4 | |
| SCHEMBL27477026 | 0.87 | ESR1 (0.53) | ESR1ESR2HSD17B3ALDH1A1CYP3A4 | |
| SCHEMBL28018022 | 0.86 | ALDH1A1 (0.47) | ALDH1A1HIF1A | |
| SCHEMBL11305185 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HIF1A | |
| SCHEMBL5385328 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HIF1A | |
| SCHEMBL28570454 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HIF1A | |
| SCHEMBL10869954 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377625-A1 | POLYCARBONATE HAVING A PRONOUNCED SHEAR THINNING BEHAVIOR | Bayer Aktiengesellschaft (DE) | 2004-01-07 | — | — | EP | disclosed |
| EP-1263856-A1 | STABILIZER COMPOSITION | BASF AKTIENGESELLSCHAFT (DE) | 2002-12-11 | — | — | EP | disclosed |
| WO-2002077065-A1 | POLYCARBONATE HAVING A PRONOUNCED SHEAR THINNING BEHAVIOR | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-03 | — | — | WO | disclosed |
| WO-2001057122-A1 | STABILIZER COMPOSITION | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-09 | — | — | WO | disclosed |